Product Name :
Dehydroeffusol
Description:
Dehydroeffusol is a phenanthrene from medicinal herb Juncus effuses. Dehydroeffusol inhibits gastric cancer cell growth and tumorigenicity by selectively inducing tumor-suppressive endoplasmic reticulum stress and a moderate apoptosis. It shows very low toxicity.
CAS:
137319-34-7
Molecular Weight:
250.29
Formula:
C17H14O2
Chemical Name:
5-ethenyl-1-methylphenanthrene-2,7-diol
Smiles :
CC1=C2C=CC3=CC(O)=CC(C=C)=C3C2=CC=C1O
InChiKey:
GSSPKCPIRDPBQE-UHFFFAOYSA-N
InChi :
InChI=1S/C17H14O2/c1-3-11-8-13(18)9-12-4-5-14-10(2)16(19)7-6-15(14)17(11)12/h3-9,18-19H,1H2,2H3
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.Talazoparib Epigenetics
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Dehydroeffusol is a phenanthrene from medicinal herb Juncus effuses. Dehydroeffusol inhibits gastric cancer cell growth and tumorigenicity by selectively inducing tumor-suppressive endoplasmic reticulum stress and a moderate apoptosis. It shows very low toxicity.|Product information|CAS Number: 137319-34-7|Molecular Weight: 250.29|Formula: C17H14O2|Chemical Name: 5-ethenyl-1-methylphenanthrene-2,7-diol|Smiles: CC1=C2C=CC3=CC(O)=CC(C=C)=C3C2=CC=C1O|InChiKey: GSSPKCPIRDPBQE-UHFFFAOYSA-N|InChi: InChI=1S/C17H14O2/c1-3-11-8-13(18)9-12-4-5-14-10(2)16(19)7-6-15(14)17(11)12/h3-9,18-19H,1H2,2H3|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: Soluble in DMSO|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.Iberdomide Apoptosis |Shelf Life: ≥12 months if stored properly.PMID:32826830 |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|Dehydroeffusol suppresses the expression of vasculogenic mimicry key gene VE-cadherin. Dehydroeffusol decreases the MMP2 expression and activity in gastric cancer cells.|References:|Zhang B, et al. Dehydroeffusol inhibits gastric cancer cell growth and tumorigenicity by selectively inducing tumor-suppressive endoplasmic reticulum stress and a moderate apoptosis. Biochem Pharmacol. 2016 Mar 15;104:8-18.Liu W, et al. Dehydroeffusol effectively inhibits human gastric cancer cell-mediated vasculogenic mimicry with low toxicity. Toxicol Appl Pharmacol. 2015 Sep 1;287(2):98-110.Products are for research use only. Not for human use.|
